Hypertonic: Mannitol 549 mmol/L Indications: Osmitrol Intravenous Infusion (Mannitol Intravenous Infusion, BP), can be used in: The promotion of diuresis, in the prevention and/or treatment of the oliguric phase of acute renal failure, before irreversible renal failure becomes established. The reduction of elevated intraocular pressure when the pressure cannot be lowered by other means; The reduction of intracranial pressure and treatment of cerebral oedema by reducing brain mass and; Promoting the urinary excretion of toxic substances. Contraindications: Osmitrol Intravenous Infusion (Mannitol BP) is contraindicated in patients with: Hypersensitivity to Mannitol Pre-existing plasma hyperosmolarity Severe heart failure Disturbance of the blood-brain barrier Well-established anuria due to severe renal disease No response to the test dose Severe pulmonary congestion or frank pulmonary oedema Active intracranial bleeding except during craniotomy Severe dehydration Progressive renal damage or dysfunction after institution of Mannitol therapy, including increasing oliguria and azotemia, and Progressive heart failure or pulmonary congestion after institution of Mannitol therapy *This product image is only for reference.
